"Warmblood" fragile foal syndrome (FFS) is a connective tissue disorder resulting in joint laxity and extremely thin skin that is only loosely connected to the body. The skin is easily torn, resulting in lacerations, hematomas, and seromas across the foal. Affected foals are euthanized shortly after birth.

Androgen Insensitivity Syndrome (AIS) is an X-linked disorder of sexual development resulting in a female horse with XY chromosomes. Horses with AIS exhibit stallion-like behavior such as agression toward other horses, Flehman response and vocalization toward cycling mares.

Cerebellar Abiotrophy (CA) is a degenerative neurological disorder, due to the death of neurons in the brain. Symptoms (head tremors, lack of coordination, wide stances, exaggerated gain, difficulty rising and startling easily), typically appear in foals between six weeks and four months of age.

Chronic Idiopathic Anhidrosis Risk (CIA) is the inability to sweat in response to increased body temperature, (AKA "non-sweater"). This condition is dangerous and sometimes life-threatening for horses, who rely on sweating for 65-70% of their temperature regulation.

Congenital Stationary Night Blindness (CSNB) is an inherited disorder in horses characterized by an inability to see in low-light or dark conditions. This condition is present from birth and does not worsen over time. Common indicators include a horse’s reluctance to enter dark environments, difficulties in locating food and water in the dark, and a propensity for nighttime injuries.

Dwarfism (DWF) is characterized by abnormal growth, leading to either a disproportionate body type or overall smaller body size. Horses with DWF often have a wide range of physical ailments and limitations, including breathing problems and eating difficulties.

Equine Arteritis Virus Resistance (EAVR) is an infectious disease with a broad range of symptoms, though most horses will not display any overt signs. Infection can result in abortion in pregnant mares, and some stallions persistently shed the virus through their semen.

Equine herpesviruses are DNA viruses that are found in most horses all over the world, often without any serious side effects. Following infection of Equine Herpesvirus Type 1 (EHV-1) some horses then suffer Equine Herpesvirus Myeloencephalopathy (EHM), which is is accompanied by serious and sometimes fatal neurological effects. EHM in horses can have serious neurological symptoms on affected horses.